csfB [2017-8-11 16:2:30]

anti-sigma factor, inhibitor of SigG and of SigE

locus: BSU00240

pI: 7.67

mw: 7.30 kDa

protein length: 64 aa

gene length: 192 bp

function: control of SigG and SigE activity

product: inhibitor of SigG and SigE

essential: no

synonyms: gin, yaaM

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.2|Control of sigma factors]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

Gene

Coordinates: 35,531 → 35,725

Phenotypes of a mutant

• premature activation of [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG] [Pubmed|17921305]

The protein

Catalyzed reaction/ biological activity

• inhibitor of [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG] [http://www.ncbi.nlm.nih.gov/sites/entrez/17921305 PubMed1] [http://www.ncbi.nlm.nih.gov/sites/entrez/19497328 PubMed2]

[SW|Localization]

• forespore and mother cell [Pubmed|25835496]

Expression and Regulation

Operons

• genes: [gene|01412FA454DDBA12622E3B32C433F8059123661B|csfB]
  description: [Pubmed|22383849]

  sigma factors

  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF]: sigma factor, [Pubmed|16497325], in [regulon|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF regulon]
  • [protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK]: sigma factor, [Pubmed|25835496], in [regulon|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|SigK regulon]

  regulation

  • expressed after completion of forespore engulfment in the mother cell ([protein|search|SigK]) [Pubmed|25835496]

Biological materials

Mutant

• MGNA-B894 (yaaM::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1893 NBRP B. subtilis, Japan]

References

• 7592342,19497328,8759874,18208527,16497325,17921305,20802044,21935351,25835496,22383849,26929302